Adipocyte-specific Gene Expression and Adipogenic Steatosis in the Mouse Liver due to PPARγ1 Overexpression*

نویسندگان

  • Songtao Yu
  • Kimihiko Matsusue
  • Papreddy Kashireddy
  • Wen-Qing Cao
  • Vaishalee Yeldandi
  • Anjana V. Yeldandi
  • M. Sambasiva Rao
  • Frank J. Gonzalez
  • Janardan K. Reddy
چکیده

The abbreviations used are: PPAR, peroxisome proliferator-activated receptor; PPRE, peroxisome proliferator response element(s); AOX, straight chain fatty acyl-CoA oxidase; L-PBE, peroxisomal enoylCoA hydratase/3-hydroxyacyl-CoA dehydrogenase bifunctional protein; PTL, peroxisomal 3-ketoacylCoA thiolase; G-6-P, glucose-6-phosphatase; C/EBPα, CCAAT enhancer-binding protein α; SREBP1, sterol regulatory element-binding protein 1; aP2, adipose fatty acid binding protein; PEPCK, phosphoenolpyruvate carboxykinase; GK, glucokinase; FAS, fatty acid synthase; MAL, malic enzyme; ACL, ATP-citrate lyase; LDLR, low density lipoprotein receptor; Glut2, glucose transporter 2; MTP, microsomal triglyceride transfer protein, ∆ d, ∆ desaturase.

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تاریخ انتشار 2002